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pH、薄荷与灼热感

Sensation depends on pH, free nicotine, moisture, pouch material, salt, flavour and contact time.

pH & free-base nicotine

Higher pH usually increases free-base nicotine and can increase buccal absorption, but pH alone does not determine sensation.

Mint, menthol & cooling agents

Menthol activates receptors including TRPM8. Low concentrations may cool; higher concentrations can irritate or burn.

NI 描述每袋所含的尼古丁量,不预测确切吸收速度或主观强度。

  1. WHO technical report on nicotine pouches
  2. Nicotine permeation, pH and oral mucosa (2025)
  3. TRP channels, nicotine irritation and menthol
  4. Oral nicotine pouch ingredients and pH